China (Mainland)
Ruxolitinib API & Intermediates CAS NO.941678-49-5
- Min.Order: 1 Gram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
- Product Details
Keywords
- Ruxolitinib
- INCB-018424
- 941678-49-5
Quick Details
- ProName: Ruxolitinib API & Intermediates
- CasNo: 941678-49-5
- Molecular Formula: C17H18N6
- Application: Ruxolitinib is a Janus kinase inhibito...
- DeliveryTime: In stock
- PackAge: Barrel sealed
- ProductionCapacity: 1000 Kilogram/Day
- Purity: ≥99%
- LimitNum: 1 Gram
Superiority
Our company has commercialized this product for long-term stable supply, the purity ≥ 99.5%. At present, our sales of this product have reached more than 480 kg.
Details
Ruxolitinib is an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation. The JAK-STAT (signal transducer and activator of transcription) pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.